We image the cortical microvasculature of anesthetized and awake Alzheimer's disease mice model using two-photon microscopy. Surprisingly, we observed a significantly increased rate of spontaneous transient capillary plugging in AD mice compared to wild-type littermates. Based on this, Mohammad's goal is to develop a new formalism to study the interaction of brain blood flow and Alzheimer's disease.
With this goal in mind, Mohammad is working on image processing and network analysis of 3D multiphoton images of brain vasculature in Alzheimer's disease using Deep Learning and other machine learning techniques. On the other hand, He investigates blood flow speeds using CFD, as he is a civil engineer by training (BS '09 & MS '11) specialized in continuum mechanics and simulations. Check out his book chapter here!
He likes to swim and enjoys reading about different schools of thought. Once upon a time, he was a volunteer certified lifeguard.